The goal of TC20 is to bring together pattern recognition scientists and life scientists to find solutions to problems in bioinformatics, and foster multidisciplinary research in the pattern recognition community.
|Elena Marchiori, Radboud University of Nijmegen, The Netherlands||-Chair|
|Alioune Ngom, University of Windsor, Canada||-Co-Chair|
|Liu Wenting, Nanyang Technological University, Singapore||-Information Chair|
|Raj Acharya, PennState, USA||- PRIB Steering Committee|
|Shandar Ahamad, Tokyo Tech NIBIO, Japan||- PRIB Steering Committee|
|Tom Heskes, Radboud University of Nijmegen, The Netherlands||- PRIB Steering Committee|
|Madhu Chetty, Monash University, Australia||- PRIB Steering Committee|
|Jagath C. Rajapakse, Nanyang Technological University, Singapore||- PRIB Steering Committee|
|Marcel Reinders,Deft University of Technology, The Netherlands||- PRIB Steering Committee|
|Dick de Ridder, Delft University of Technology, The Netherlands||- PRIB Steering Committee|
|Guido Sanguinetti, University of Edinburgh, United Kingdom||- PRIB Steering Committee|
|Visakan Kadirkamanathan, University of Sheffield, UK||- PRIB Steering Committee|
|Jun Sese, Tokyo Tech NIBIO, Japan||- PRIB Steering Committee|
Goal The goal of TC20 is to bring together pattern recognition scientists and life scientists to find solutions to problems in bioinformatics, and foster multidisciplinary research in the pattern recognition community. In order to achieve its goal, TC-20 will expand its activities in the following areas: Education: through the website, educational materials such as lecture notes, tutorials, etc., will be made available. Research: a database of bioinformatics applications, literature, tools, and benchmark datasets will be maintained. Events: organize PRIB conferences, special sessions at conferences, special issues of journals, and competitions, etc.
Background The past decade has witnessed an explosion and implosion of the amount and complexity of bioinformatics data such as DNA and protein sequences, gene and protein expressions, structures, pathways, genetic information, biomedical text data, and molecular images. Although the analyses of these data involve pattern recognition and data mining, novel and efficient data analysis techniques are yet to be discovered to realize their true potential. Bioinformatics is aimed at discovering knowledge from life sciences data with the aid of Information Technology, to find answers to unresolved problems in biology. One of the important discoveries of pattern recognition in bioinformatics is that specific patterns of our genomes and proteomes are able to tell our characters and how prone we are for certain diseases. In the coming years, medical practitioners will be able to personalize our medication by just looking at these patterns.
Research Interests Pattern recognition in the following areas:
- Computational and comparative genomics
- Functional genomics
- Structural genomics and proteomics
- Cheminformatics, chemigenomics
- Systems biology, pathway analysis
- Synthetic biology
- Pharmacogenomics, drug discovery
- Medical informatics
- Biological imaging
Pattern Recognition for Bioinformatics DNA molecules store the blueprint of cell function. Information stored in DNA, a chain of four nucleotides (A, T, G, and C), is first transcribed to mRNA and then translated to the functional form of life, proteins. The initiation of translation or transcription process depends on the presence of specific signals and patterns, referred to as motifs, present in DNA and RNA. Research on in silico detection of specific patterns of DNA sequences such as genes, binding sites, and promoters, leads to better understanding of molecular level function of a cell. Comparative genomics focus on comparison of different genomes to find conserved patterns or significant mutations over the evolution, which could possess some functional significance. Construction of evolutionary trees is useful to infer how genome and proteome are evolved and branch across species by ways of a complete library of motifs and genes. A protein’s functionality or interaction with other proteins is mainly determined by its 3-D structure. Prediction of protein’s 3-D structure from its 1-D amino-acid sequence remains an important problem in structural genomics; protein-protein interactions are responsible for most molecular functions in living cells. Computational modeling and visualization tools of 3-D structures of proteins and interaction help biologists to infer cellular activities. The challenge in functional genomics is to analyze gene expressions accumulated by microarray techniques to discover co-regulated genes and thereby gene regulatory networks. Discovering and understanding how genes and proteins interact in specific pathways are gateways to systems biology. Molecular and cellular imaging provides techniques for in vivo sensing or imaging of cellular events such as movement of cells and subcellular localization of proteins. Potential techniques to fuse and integrate different types of life sciences data are yet to be realized. The ever expanding knowledge of biomedical and phenotype data, combined with genotypes, is becoming difficult to be analyzed by traditional methods. Advanced data mining techniques, where the use of metadata for constructing precise descriptors of medical concepts and procedures, are required in the field of medical informatics. The vast amount of biological literature is posing new challenges in the field of text mining. These text mining techniques along with the aid of information fusion methods could help find pathways and interaction networks. Today, high throughput and high content screening techniques allow biologists to gather data at an unprecedented rate. However, pattern recognition techniques to make inferences from these data are not evolving at a rate sufficient to meet the demand.
PRIB Conference International Conference on Pattern Recognition in Bioinformatics (PRIB) is the major event of TC-20.
- PRIB 2013, Nice, France
- PRIB 2012, Tokyo, Japan
- PRIB 2011, Delft, The Netherlands
- PRIB 2010, Nijmegen, The Netherlands
- PRIB 2009, Sheffield, UK
- PRIB 2008, Melbourne, Australia
- PRIB 2007, Singapore
- PRIB 2006, Hong Kong, China
PRIB Conferences are held under the guidance of PRIB Steering Committee. Your proposal to hold PRIB in 2013 should be sent to the PRIB Secretariat and will be evaluated by the Steering Committee. The PRIB Committee membership is open to the participants of PBIR conferences. Enquiries on IAPR TC-20 or PRIB Membership should be directed to the PRIB Secretariat.
The important factor of PRIB Papers is 1.84 (see details) according to Publish or Perish 3.